Two efflux systems expressed simultaneously in multidrug-resistant Pseudomonas aeruginosa.
نویسندگان
چکیده
Simultaneous overexpression of MexAB-OprM and MexEF-OprN was demonstrated for a multiply antibiotic-resistant clinical isolate of Pseudomonas aeruginosa (G49). G49 also had decreased expression of OprF. No mutations in mexR or its upstream promoter region, mexT, oprM, oprF, or sigX were revealed, suggesting regulation by a hitherto undescribed locus.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 44 10 شماره
صفحات -
تاریخ انتشار 2000